Sciatica Patients Under Chiropractic Less Likely to have Opioid-Related Adverse EventsA large study published on January 28, 2025, in the PLOS ONE journal, showed that patients who were suffering with sciatica and selected chiropractic care were less likely to suffer Opioid-Related Adverse Events (ORADEs) as compared to those who did not receive chiropractic. The study was conducted by researchers at the University Hospitals Connor Whole Health in Cleveland, Ohio.
An article on this study was released in the publication, Medical Press, on January 29, 2025, and gave an overview of the study by saying "A new study led by researchers at University Hospitals Connor Whole Health found that adults with newly diagnosed sciatica who initially received chiropractic spinal manipulation (CSM) were significantly less likely to experience opioid-related adverse drug events (ORADEs) such as overdose and poisoning over a one-year follow-up compared to those receiving usual medical care."
The researchers in this study reviewed 216 million patient records between 2009 and 2024 in order to create two groups for the study. All patients in this study were suffering with sciatic pain and were over the age of 18 years. Patients were excluded from being included in this study if they had previously had spinal surgery, a history of prior anesthesia, any serious type of pathology, or were at a higher risk of addiction or reactions from opioid drugs.
After ruling out millions of cases from being included in this study, the remaining cases were divided into two matching groups of 372,471 patients in each. One group received standard medical care while the other group received chiropractic care, referred to by the researchers as "chiropractic spinal manipulation (CSM)."
The results of the study showed that the group that received chiropractic care was three times less likely to have opioid-related adverse drug events (ORADEs) as compared to the group that had standard medical care.
In commenting on this study, Dr. Françoise Adan, Chief Whole Health and Well-being Officer and Director of UH Connor Whole Health stated, "In light of the ongoing opioid crisis, these findings underscore the importance of offering evidence-based non-pharmacological alternatives for pain management."
Lead author Robert Trager, DC, also commented in the Medical Press article when he added, "Although previous studies demonstrated a reduced likelihood of opioid prescription among patients receiving chiropractic care, our study is the first to focus on opioid-related adverse events, adding a layer of clinical relevance to our work."
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